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Frank was not in season one.
Frank moves in with Charlie and offers to help pay his rent. Frank having grown disillusioned with his rich yuppie lifestyle wants to live in squallor like he used to. Frank sleeps with the two strippers Mac and Charlie were planning to sleep with by locking them out of Charlie's apartment. (Charlie Gets Crippled)
Frank puts all of his money in Charlie's bank account to hide it from his wife Barbara Reynolds. Mac and Charlie spend the money on hookers. Frank is impressed with Charlie's guts and promotes him to manager. (Dennis and Dee Go on Welfare)
Frank sleeps with Charlie's crush the Waitress. (Mac Bangs Dennis' Mom)
Charlie and Frank become obsessed with trash and bring everything they can find back to their apartment. Frank is adamant that he is not Charlie's father because Charlie's mom had an abortion. He insists that Bonnie must have gotten pregnant after she banged some dude after the abortion. Charlie discovers that Bonnie had the abortion but Charlie survived. Bonnie says she had to keep it a secret from Frank because he was married to Barbara Reynolds at the time. If he had found out he would have made Bonnie throw him in a dumpster. Charlie then becomes convinced that the dumpster baby Dee and Mac found is really Frank and the Waitress' son even though they had only slept together 3 months earlier. The Waitress calls child protective services. (The Gang Finds a Dumpster Baby)
Frank laces Charlie's beer with LSD thus turning him into his alter ego Green Man. (The Gang Gets Invincible)
When the gang gets held hostage by the McPoyles Frank enlists Mac to make sure Charlie dies so he can't inherit his fortune. Charlie destroys the will. (The Gang Gets Held Hostage)
Frank and Charlie conduct their own investigation into whether or not Mac is a serial killer, with Frank breaking and entering, wanting to torture Mac with a chainsaw, and so on, while Charlie tries to be the lawyer and point out Frank's lack of evidence and such (Mac Is a Serial Killer).
Frank moves out of their apartment and moves in with Charlie's mom Bonnie Kelly, who becomes his new "bang maid" handing out massages and handjobs like hotcakes. Charlie is jealous of his mother stealing Frank away from him. He plots to make Bonnie fall in love with Mac's drug dealer father Luther Mac so he can have Frank back. (Dennis Looks Like a Registered Sex Offender)
After Charlie and Dee steal his deer steak Frank tricks them into eating raccoon meat and makes them think it's human meat. (Mac and Dennis: Manhunters)
Frank is devastated when Mac and Charlie fake their deaths, even carrying a mannequin of Charlie around, speaking to it and even at one point "banging" it. (Mac and Charlie Die (Part 2))
Frank and Charlie argue over who pooped the bed. It turns out to be Frank. (Who Pooped the Bed?)
Charlie and Frank become crab fishermen. (The Great Recession)
This season revealed them to be very close best friends, referring to themselves as the "Gruesome Two-some." (Mac and Dennis Break Up)
Charlie convinces Frank to enter into a same sex marriage so he can get on Frank's insurance. (Mac Fights Gay Marriage)
Charlie and Frank walk around naked in the sewers together. (Dee Gives Birth)
Frank and Charlie, along with the rest of the gang, sleep in the bar to stay safe during a hurricane. Frank and Charlie sleep in a double sleeping bag together. (The Storm of the Century)
Frank tells a boatload of tourist," Charlie, he's my buddy, we sleep together, we hang out together." (Thunder Gun Express)
- Charlie and Frank call themselves the "Gruesome Twosome". (Mac and Dennis Break Up)